Ultrasound Guided Transversus Abdominis Plane Block in Major Gynaecological Surgery – A randomised controlled Trial

A randomised placebo-controlled double-blind trial assessing the analgesic efficacy of ultrasound guided transversus abdominis plane local anaesthetic block in major gyanae-oncological surgery

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12608000161325

Enrollment

Registered

2008-04-03

Start date

2008-12-03

Completion date

2009-10-07

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The project aims to demonstrate that transversus abdominis plane block is an effective adjunct to multi-modal analgesia in the setting of major gynaecological surgery via midline laparotomy. The project aims to demonstrate that the technique improves overall pain relief, reduces morphine consumption (and opioid side effects) and improves patient satisfaction.

Interventions

Ultrasound guided transversus abdominis plane (TAP) local anaesthetic blockade. This involves two injections of 20ml 0.5% ropivicaine (total 40ml). The injections take around 10 minutes to perform.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Adult females scheduled to undergo laparotomy via midline incision for known or suspected gynae-oncology

Exclusion criteria

inability/unwillingness to provide informed consent, allergy/sensitivity to any of the protocol medications, patient or treating anaesthetist preference to use epidural (or other) analgesia

Outcome results