Acute alerting effects of daytime exposure to specific wavelengths of light

The effectiveness of exposure to different colours of light in improving alertness and psychomotor vigilance in sleep restricted and non-sleep restricted healthy adult participants

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12608000142336

Enrollment

120

Registered

2008-03-19

Start date

2008-01-21

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study examines the effects of different colours of light on sleepiness and performance on various tasks. It is predicted that exposure to blue light will reduce sleepiness and improve performance more effectively than other colours of light.

Interventions

Intervention: Ocular exposure to specific monochromatic wavelengths of light administered using a specialised light delivery system. For three hours, each participant will be exposed to one of the following wavelengths of light: violet light (420nm), blue light (460nm), green light (555nm), or red light (620nm).

Study design

Allocation

Randomised controlled trial

Intervention model

Factorial

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

18 Years to 30 Years

Healthy volunteers

Yes

Inclusion criteria

(1) Male and female adults aged 18 to 30 years inclusive (2) Healthy

Exclusion criteria

(1) Individuals who have engaged in shiftwork/nightwork in the past 3 years and/or transmeridian travel in the past 3 months. (2) Individuals who smoke, report high caffeine intake and/or high alcohol consumption. (3) Individuals who screen positive for drugs of abuse following comprehensive urine toxicological analysis. (4) Women who are pregnant, lactating or planning to become pregnant during the study period. (5) A history of alcohol/drug dependence. (6) Current, recent (<3 months) or chronic history of use of drugs or medication that affect the central nervous system (except non-steroid topical creams, oral contraceptives and occasional use of mild pain killers. (7) History of psychiatric illness. (8) Recent acute or chronic medical illness. (9) Abnormal sleep patterns/sleep disorders. (10) Auditory defects. (11) Any form of photophobia including drug-induced, epilepsy, seizures, vertigo or migraine. (12) Individuals with diseases of the visual system. (13) Females who are not taking a medically approved form of birth control.

Outcome results