Effects of a Chinese herbal preparation containing Radix Polygoni Multiflori and Radix Salviae Miltiorrhizae on cardiovascular disease risk

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12608000133336

Enrollment

Registered

2008-03-14

Start date

2003-10-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This parallel double-blinded and randomised placebo controlled study examined effects of He Shou Wu Capsule (HSWC), a pharmaceutical preparation derived principally from the Chinese herbs Radix Polygoni Multiflori, Radix Salviae Miltiorrhizae, on a range of cardiovascular disease risk factors in subjects with mild to moderate hypercholesterolemia.

Interventions

Treatment with a Chinese medicine herbal preparation, the He Shou Wu Capsule (containing four Chinese herbs) in capsule form, 1 packet of capsules three times/day (oral administration) for 12 weeks.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Prevention

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Healthy individuals aged 18 years and over with a total plasma cholesterol of 5.0 mmol/L or above, triglyceride level of greater than 2 mmol/L or high density lipoprotein (HDL) cholesterol level of less than 1.0 mmol/L

Exclusion criteria

Exclusion criteria included: plasma triglyceride levels over 10 mmol/L, established heart disease, other serious medical or psychological conditions, pregnancy, current use of vasoactive medications, warfarin, and postmenopausal hormone therapy.

Outcome results