Effects of a herbal preparation containing Radix Salviae Miltiorrhizae, Radix Notoginseng and Borneolum Syntheticum on circulating adhesion molecules and cardiovascular risk

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12608000132347

Enrollment

Registered

2008-03-14

Start date

2003-10-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

A parallel double blind randomised placebo-controlled study was conducted to assess the effects of a Chinese herbal medicine, the Dantonic Pill, on circulating adhesion molecules in participants with mild-moderate hypercholesterolemia.

Interventions

Chinese herbal medicine treatment: combination of three Chinese herbs (Radix Salviae Miltiorrhizae, Radix Notoginseng and Borneolum Syntheticum) in capsule form, oral administration, 1 packet of capsules three times/day for 12 weeks.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Prevention

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Healthy individuals aged 18 years and over with a total plasma cholesterol of 5.0 mmol/L or above, triglyceride level of greater than 2 mmol/L or high density lipoprotein (HDL) cholesterol level of less than 1.0 mmol/L.

Exclusion criteria

Exclusion criteria included plasma triglyceride levels over 10 mmol/L, established heart disease, other serious medical or psychological conditions, pregnancy, current use of vasoactive medications, warfarin, and postmenopausal hormone therapy.

Outcome results