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A trial of inhaled heparin in patients with acute lung injury

A phase 2 randomised blinded trial of nebulised heparin in patients requiring mechanical ventilation for more than 48 hours

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12608000121369
Enrollment
50
Registered
2008-03-05
Start date
2008-04-04
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

To investigate if nebulised heparin improves oxygenation of patients with acute lung injury

Interventions

Inhaled heparin (5 ml) will be given daily for 14 days or until extubation

Sponsors

St.Vincent's Health
Lead SponsorHospital

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)

Eligibility

Sex/Gender
All
Age
15 Years to 90 Years
Healthy volunteers
No

Inclusion criteria

Has or at high risk of developing acute lung injury

Exclusion criteria

At risk of pulmonary hemorrhage Allergy to heparin

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026