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Gait, balance and falls risk in people with knee osteoarthritis before and after knee replacement surgery

Gait, balance and falls risk in people with knee osteoarthritis before and after knee replacement surgery

Status
Not yet recruiting
Phases
Phase 1
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12608000116325
Enrollment
60
Registered
2008-02-29
Start date
2008-06-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Falls are among the most common cause of injury and hospital admissions in older people in Australia, and due to the ageing of the population, are a major public health concern. The detection of factors associated with falls may allow clinicians and professionals to implement effective falls prevention programs targeted to those at greatest risk, such as older people with knee osteoarthritis (knee OA). This study will assess the falls risk of individuals with knee osteoarthritis before and at 4 and 12 months following knee replacement surgery using the a series of validated tests (the Physiological Profile Assessment). Additionally, this study will investigate walking patterns (including the minimum foot clearance and the swing limb kinematics and kinetics) in patients with knee osteoarthritis (prior to undergoing knee replacement and 4 and 12 months following surgery) and compare them to an asymptomatic age-matched control group. As such this study will identify the balance and gait characteristics that may predispose older people with knee osteoarthritis to tripping and falling. The research hypotheses are: (i) Patients with knee osteoarthritis will demonstrate different falls risk before and after knee replacement. (ii) Patients with knee osteoarthritis will demonstrate altered minimum toe clearance and swing limb mechanics compared to age matched controls. (iii) Patients with knee osteoarthritis will show different minimum toe clearance and swing limb biomechanics before and after knee replacement surgery.

Interventions

participants with end stage of knee osteoarthritis (on a waiting list for knee surgery) will be assessed before undergoing knee replacement surgery and after knee replacement surgery for a follow up of 1 year.

Sponsors

Musculoskeletal Research Centre, La Trobe University
Lead SponsorUniversity

Study design

Allocation
Non-randomised trial
Intervention model
Parallel
Primary purpose
Prevention
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
18 Years to 95 Years
Healthy volunteers
No

Inclusion criteria

patients with diagnosed unilateral or bilateral medial compartment knee OA (on a waiting list for knee replacement) aged 50 and over (of either gender)

Exclusion criteria

Patients will be excluded if they had uncontrolled systemic disease, previous knee surgery and a pre-existing neurological or other orthopaedic condition affecting walking. Participants will be also excluded from the study if they have had the following foot conditions: partial foot amputation or ulceration, foot fractures, any neurological condition that affects lower limb strength (eg: stroke, polio), or any other musculoskeletal conditions which may affect the foot (eg: rheumatoid arthritis, gout).

Outcome results

None listed

Source: ANZCTR · Data processed: Mar 25, 2026