None listed
Conditions
Brief summary
The role of tepid sponging to promote fever control in children is controversial. We did not find studies reporting the effectiveness of tepid sponging in addition to dipyrone. The aim of this study is to compare the effects of tepid sponging plus dipyrone with dipyrone alone in reducing fever. This randomized clinical trial will take place at Instituto Materno-Infantil Professor Fernando Figueira, Teaching Hospital, Recife, Pernambuco. Children from 6 months to 5 years old with axillary temperature > 38 C in the emergency ward between January and July 2006 are eligible. One hundred-twenty children will be randomly assigned to receive oral dipyrone (20 mg/Kg) or oral dipyrone and tepid sponging during 15’. The primary outcome is the mean temperature reduction after 15, 30, 60, 90 and 120 minutes. Secondary outcomes are crying and irritability.
Interventions
Dipyrone (20 mg/Kg) oral syrup by mouth at the beginning of the study and tepid sponging during 15 minutes
Sponsors
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
6 Months to 60 Months
Healthy volunteers
No
Inclusion criteria
Children attended between 5:00 h p.m and 7:00 h p.m. and aged from 6 to 60 months with an axillary temperature of between 38.5 C and 40 C and a clinical diagnosis consistent with upper respiratory tract infections (URTI). Able to stay in the emergency ward for at least two hours.
Exclusion criteria
Requiring admission, urgent investigation or emergency treatment and those who had received antipyretic, steroids or non-steroidal anti-inflammatory drugs (NSAIDs) during the previous six hours were excluded, as where children with known liver or renal diseases, gastrointestinal bleeding, known allergy to dipyrone, congenital or acquired immunodeficiency or malignancy
Outcome results
None listed