An investigation of the effect of vitamin D supplementation on insulin resistance and bone health in South Asian women

The effect of vitamin D supplementation on insulin resistance and bone markers in South Asian women with hypovitaminosis D and raised insulin resistance (HOMA-IR)

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12607000642482

Acronym

Surya Study

Enrollment

100

Registered

2007-12-17

Start date

2007-02-15

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

People of South Asian origin are anecdotally thought to be deficient in vitamin D, partly due to skin colour and partly to other lifestyle/cultural reasons. They are also known to be at greater risk of developing type 2 diabetes than the general population. There is some evidence that vitamin D deficiency plays a role in the aetiology of diabetes. The aim of this trial is to test the hypotheses that insulin resistance will improve when vitamin D deficiency is addressed.

Interventions

Vitamin D (25(OH)D3) supplement, 4000 international units (IU) per day in the form of an oral capsule, for 6 months. Vitamin D is synthesised in the skin in the presence of sunlight, but can also be taken as a dietary supplement.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Prevention

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

20 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

Female, South Asian

Exclusion criteria

Vitamin D supplements >1000IU per day, medicated for diabetes, chronic kidney disease

Outcome results