None listed
Conditions
Brief summary
The purpose of this study is to examine the post operative efficacy and safety of NRT initiated in patients admitted to hospital for coronary artery bypass surgery. We hypothesise that commencing NRT in the immediate post operative phase will be well tolerated by patients, lead to fewer withdrawal symptoms and greater quit rates at 6 months. This pilot randomised control trial is expected to validate the feasibility of conducting a larger scale multi-centre trial that will generate evidence to support the use of NRT as an inpatient initiated secondary prevention strategy in post-operative bypass patients.
Interventions
Transdermal nicotine patch. 10 week programe of nicotine patch starting at 21mg for 6 weeks, 14 mg for 2 weeks, 7mg of 2 weeks.
Transdermal nicotine patch contains nicotine which is absorbed through the skin.
Sponsors
University of Adelaide
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Current smoker, admitted to hospital for coronary artery bypass grafting.
Exclusion criteria
Recent myocardial infarction ( within 3mths prior to recruitment). Suffer from unstable angina. Has suffered a cerebrovascular accident (CVA). Hypersensitivity to nicotine, menthol or adhesive tapes. History of substance abuse in the previous 12mts.
Outcome results
None listed