Comparison of fasting glucose and oral glucose tolerance testing to screen for diabetes mellitus in subjects on long-term glucocorticoid therapy

Status

Completed

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12607000540415

Enrollment

118

Registered

2007-10-22

Start date

2007-10-22

Completion date

2011-04-29

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The primary purpose of this study is to determine the prevalence of diabetes in subjects on long-term glucocorticoid (steroid) therapy and the best way to diagnose diabetes in this patient group.

Interventions

Oral glucose tolerance test: This involves a blood test to measure plasma glucose fasting and 2 hours after a 75 g glucose drink. The test takes two hours.

Eligibility

Sex/Gender

All

Age

30 Years to -2147483648 No limit

Healthy volunteers

Inclusion criteria

Long-term glucocorticoid therapy (> 6 months)

Exclusion criteria

Type 1 diabetes mellitus Active inflammatory disease (defined as clinical evidence of active synovitis, elevated C-reactive protein (CRP) or recent intensification of immunosuppressive therapy) Significant hepatic (AST or ALT > 3 times upper limit of normal) or renal (serum creatinine > 200µmol/L) dysfunction

Outcome results