Measuring ovarian reserve in women having laparoscopic surgery.

Anti-Mullerian Hormone measurement as a measure of ovarian reserve in women having a unilateral ovarian cystectomy

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12607000523404

Acronym

N/A

Enrollment

Registered

2007-10-11

Start date

2007-08-10

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Informed consent obtained to take blood tests for AMH level estimation before surgery andat 2 time points afterwards

Interventions

Ovarian reserve is an estimate of the number of oocytes in the ovary. Anti-mullerian Hormone is thought to be one of the best measures of ovarian reserve. Despite this the assay is not widely available and Adelaide is the only city in Australia that provides this test mainly in a research setting. It is not routinely used to assess ovarian reserve after ovarian surgery. A blood test for Anti-mullerian hormone will be taken immediately prior to surgery then at 6 weeks and 3 months after surger

Eligibility

Sex/Gender

All

Age

13 Years to 45 Years

Healthy volunteers

Inclusion criteria

1)women with regular natural menstrual cycles or on COC contraceptive Women on the combined oral contraceptive can be included as recent data shows that AMH levels are not altered by the pill. 2)women undergoing an laparoscopic gynaecological procedure. The inclusion criteria has been modified to include women more than 13 years of age who are having natural menstrual cycles and can give informed assent with parental consent.

Exclusion criteria

1) women unable or unwilling to independently give informed consent to participate in this study. 2)Women on medications that interfere with AMH levels. 3)Women with polycystic ovarian syndrome (AMH levels are high) 4)Women with malignant pathology. 5)Women who are deemed unsuitable to participate in this study as assessed by their lead clinician.

Outcome results