None listed
Conditions
Brief summary
The purpose of this project is to determine what is the most appropriate method of investigation of lung masses, or suspected lung cancer. Currently there is no guidance for clinicians as to which of the two commonest methods (bronchoscopy or CT-guided lung biopsy) is optimal. Our study hopes to determine if one of these two diagnostic procedures is more appropriate than the other in investigating patients with lung masses or suspected lung cancer. While either may be performed at present, there is no information to guide clinicians as to particular clinical features that may make one procedure more beneficial than the other, both in terms of maximizing the rate of achieving a diagnosis and also in minimizing the rate of complications.
Interventions
Patients will be randomized to undergo either Endobronchial Ultrasound or CT-guided core needle biopsy for the investigation of lung nodules/suspected lung cancer. Once the procedure (each will take approximately 20 minutes to perform) is completed their involvement in the trial will conclude.
Sponsors
Royal Melbourne Hospital
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Diagnosis
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
-2147483648 No limit to -2147483648 No limit
Healthy volunteers
No
Inclusion criteria
All patients referred to multidisciplinary lung clinic for evaluation and investigation of a solitary pulmonary nodule OR suspected lung cancer
Exclusion criteria
1.clinical condition precludes investigation 2.Lesions <2cm diameter within 1cm of pleura 3.lesion <1cm diameter anywhere in lung fields 4.Evidence on CT scan of central (endobronchially visible) lesion 5.Other clinical site of disease more amenable to tissue diagnosis 6.Tissue diagnosis considered unnecessary by MDC team 7.Known current diagnosis of lung cancer
Outcome results
None listed