Pharmacokinetics of Azithromycin in pregnancy

Measurement of the pharmacokinetic parameters of Azithromycin in pregnant women to evaluate its potential use in preventing malaria in this population.

Status

Not yet recruiting

Phases

Phase 1

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12607000442404

Enrollment

Registered

2007-08-31

Start date

2007-10-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Azihromycin 1.5g daily for two days in combination with with either: 1) Chloroquine 10mg/kg daily for three days -or- 2) Sulphadoxine/Pyrimethamine (SP) 25mg/1.25mg per kg as a single dose on the first day

Study design

Allocation

Randomised controlled trial

Primary purpose

Prevention

Eligibility

Sex/Gender

All

Age

-2147483648 N/A to -2147483648 N/A

Healthy volunteers

Yes

Inclusion criteria

Pregnancy Melanesian

Exclusion criteria

Severe malaria Severe anaemia Pregnancy associated complications

Outcome results