None listed
Conditions
Brief summary
Knee pain is a common problem with 19-23% prevalence in people aged 40 and over. Frankston hospital has 138 patients awaiting knee replacement and a waiting time exceeding 18 months. Preliminary work suggest patient with anterior, medial and lateral compartment knee pain who have not had open knee surgery may obtain good but temporary pain relief and functional improvement from selectively anaesthetising the cutaneous nerves supplying the knee joint. This study seeks to validate the injection technique, determine which nerves need to be injected and which patients, pain patterns and pathology may benefit from this treatment or may benefit from a follow-on study of pulse radiofrequency treatment to these nerves.
Interventions
Double blind Randomised selective subcutaneous nerve blocks with local anaesthetic or normal saline in 0.5mL aliquots upto maximum 10 mL for complex knee pain in patients awating knee replacement. The trial involves 1 set of injections with the study drug and upto 2 sets of injections with open label 1% lignocaine to determine if pain can be relieved and the duration of pain relief.
Sponsors
Dr Murray Taverner
Study design
Allocation
Randomised controlled trial
Intervention model
Other
Primary purpose
Treatment
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
18 Years to -2147483648 No limit
Healthy volunteers
No
Inclusion criteria
Waiting list patients with painful knee(s) rated >=5/10 on Verbal Rating Scale (VRS)awaiting knee arthroplasty
Exclusion criteria
Subject on waiting list for a revision knee replacement, has terminal cancer or is unable to communicate or refuses to participate.
Outcome results
None listed