The Effect of the Antioxidant (GliSODin) on Unexplained Fatigue

Evaluation of an orally-bioactive form of Superoxide Dismutase, GliSODin, in reducing levels of fatigue in otherwise healthy women aged between 50-65 years over a 12-week period.

Status

Completed

Phases

Phase 1

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12607000420448

Enrollment

Registered

2007-08-21

Start date

2007-07-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Fatigue is a common problem and in many cases its cause cannot be medically explained. An understanding of the biochemical processes humans use to generate energy within the cells leads to a hypothesis to explain the cause of some forms of fatigue based on defective cellular energy processes. The active substance used in this study, GliSODin contains Superoxide Dismutase, an enzyme which may assist in the normal biochemical production of energy in human cells.

Interventions

Superoxide dismutase enzyme in an orally-bioactive form, 250mg daily for 12 weeks. The capsule contains 3.11mg melon extract in a base of maltodexrtin.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

50 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

Unexplained fatigue of greater than 3 months' duration

Exclusion criteria

Clinical Depression, Diagnosed Thyroid Disorder, Iron-deficiency anaemia, Coeliac Disease, Any serious disease, History of Alcohol or Drug Abuse, Primary Sleep Disorder

Outcome results