Is 3 minutes of CPR before defibrillation, better than immediate defibrillation, for patients who are found to be in cardiac arrests by paramedics?

In patients who are found by paramedics to be in cardiac arrests due to Ventricular Fibrillation, is 3 minutes of Cardiopulmonary Resuscitation before defibrillation superior to immediate defibrillation when examining survival to hospital discharge.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12607000401459

Acronym

CBD Study

Enrollment

300

Registered

2007-08-06

Start date

2005-07-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The primary aim of the study is to determine whether 3 minutes of CPR before defibrillation is more effective than the standard procedure of immediate defibrillation in helping patient who are in cardiac arrest in the out-of-hospital environment to survive to hospital.

Interventions

Following the first defibrillation standard cardiac arrest guidelines are reverted to. The duration of study is until either death is declared on scene, death occurs in hospital or the patient survives to hospital discharge.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Exclusion criteria

Cardiac arrest due to trauma, witnessed cardiac arrest, clinical intervention (intubation or drugs) applied before arrival of paramedics (bystander CPR is not exclusion criteria), not for resuscitation order or similar documentation/wishesinclusion: out-of-hospital cardiac arrest found to be in ventricular fibrillation by the first paramedics on scene.

Outcome results