The long term effect of inhaled hypertonic saline (6%) in non-cystic fibrosis bronchiectasis.

The long term effect of inhaled hypertonic saline (6%) on pulmonary exacerbations, quality of life and lung function in patients with non-cystic fibrosis bronchiectasis.

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12607000367448

Enrollment

Registered

2007-07-13

Start date

2007-12-20

Completion date

Unknown

Last updated

2026-03-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The main purpose of this study is to determine whether the long term inhalation of a salt solution will decrease the number of lung infections and improve the quality of life of people with bronchiectasis.

Interventions

Hypertonic saline (6%) - 5mls nebulsied twice a day for 12 months

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Diagnosis of bronchiectasis using high resolution computer tomography (HRCT), at least two pulmonary exacerbations over past year, producing sputum daily, stable clinical state

Exclusion criteria

Cystic fibrosis, clinically unstable, unable to tolerate hypertonic saline (6%)

Outcome results