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Transcutaneous Pulse Radiofrequency Treatment for Knee Pain

Transcutaneous Pulse Radiofrequency treatment to relieve pain of knee osteoarthritis.

Status
Not yet recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12607000351415
Enrollment
40
Registered
2007-06-29
Start date
2007-08-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The aim of this follow-on study is to determine if a transcutaneous pulse radiofrequency treatment can provide useful pain relief in patients with complex knee pain awaiting knee arthroplasty. Knee pain is a common problem with 19-23% prevalence in people aged between 40 and 79 years. An earlier study has shown some patients awaiting knee replacement surgery obtain good pain relief and functional improvement from selective nerve blocks lasting several weeks or months. This however still leaves a significant number of patients experiencing pain while waiting for surgery and other strategies need to be explored. Favourable outcomes have been reported from case series of transcutaneous pulse radiofrequency treatment described in conference proceedings and the literature. Transcutaneous PRF is a painless, non-invasive, non-destructive, needle-free alternative treatment that applies a pulsing electrical field around the target nerve using TENS electrodes that ‘stuns’ rather than destroys the nerve, rendering the nerve incapable of transmitting pain signals. It is not known how transcutaneous PRF works, however, it is thought to induce long lasting biochemical changes in the target spinal nerves without disrupting sensation or motor function. Treatment can be repeated if there is a good response to the first transcutaneous PRF. 40 knee arthroplasty waiting list patients rating their knee pain =5/10 on a verbal rating scale will be invited to participate in a DBRPC trial of transcutaneous pulse radiofrequency treatment. Patients with awaiting a revision hip replacement, with hip or ankle pain interfering with walking, terminal cancer, unable to communicate in English or don’t want to participate will be excluded. The outcome will be determined by comparing pre and post transcutaneous pulse radiofrequency treatment self report questionnaires and objective physical measures

Interventions

Double Blind Randomised Control Trial of Active (5 two-minute 20ms 2Hz 80V in one treatment session) and Inactive (5 two-minute 0V in one treatment session) Transcutaneous Pulse Radiofrequency Treatment For Knee Pain in patients awaiting knee replacement surgery.

Sponsors

Dr Murray Taverner
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Waiting list patients with painful knee(s) rated >=5/10 on a verbal rating scale awaiting knee arthroplasty.

Exclusion criteria

Subject on waiting list for a revision knee replacement, or with ipsilateral hip or ankle pain interfering with walking.Subject has terminal cancer, is unable to communicate or refuses to participate.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026