An observational study looking at the relationship between upper gut function and diarrhoea in Intensive Care patients

Diarrhoea in the critically ill: A Cohort study of the association between gastro-duodenal motility and diarrhoea

Status

Completed

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12607000348459

Enrollment

Registered

2007-06-28

Start date

2007-07-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This is an examination of data, previously collected, to assess if, in patients on a ventilator in the intensive care unit, there is an association between abnormal function of the stomach and duodenum and the number of patients with diarrhoea.

Interventions

Prevalence of diarrhoea will be observed for 7 days post a motility study (a antro-pyloro-duodenal motility study) during enteral nutrition. Specifically an assessment of: i) Abnormal phase III activity during gastric feeding ii) Abnormal Characteristics of the MMC (migrating motor complex) and iii) proportion of each cycle (Quiescent, irregular or burst) and the association between diarrhoea

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Ventilated critically ill patients.

Exclusion criteria

Contraindication to endoscopy (unstable c-spine or raised intra cranial pressure) previous upper GI (gastrointestinal) surgery. Laparotomy this admission. Contraindication to use of sedation.

Outcome results