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Cardiovascular health and coenzyme Q10.

Study to compare vascular function, cardiovascular risk markers and plasma coenzyme Q10 levels in statin-treated patients with familial hypercholesterolemia versus statin-treated patients without familial hypercholesterolemia and healthy controls

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ANZCTR
Registry ID
ACTRN12607000341426
Enrollment
90
Registered
2007-06-26
Start date
2007-07-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study aims to compare plasma CoQ10 levels and cardiovascular measurements in patients with and without inherited high cholesterol levels and are on statin therapy and healthy volunteers. If people receiving statin treatment have lower CoQ10 levels and less favourable cardiovascular risk measurements it would suggest that they may benefit from CoQ10 supplementation, in combination with their statin therapy, to further reduce cardiovascular risk.

Interventions

None listed

Sponsors

Lipid and Diabetes Research Group
Lead SponsorOther

Eligibility

Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

Patients with inherited high cholesterol levels and patients with high cholesterol levels that are not inherited currently taking statin medication at a dose of at least 40mg/day for at least 3 months. Healthy volunteers: Population average cholesterol levelsExclusion criteria: Taking coenzyme Q10 supplements, history or cardiovascular disease, diabetes, any other serious existing health problems

Exclusion criteria

Taking coenzyme Q10 supplements, cardiovascular disease requiring treatment or surgery within the last 3 months

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026