None listed
Conditions
Brief summary
This is a study of implantation of marker seeds into the prostate to assess the feasibility of using marker seeds to locate the prostate before daily radiotherapy treatment for men with localised prostate cancer. Who is it for? You can join this study if you are a man aged 50–80 years with localised prostate cancer and you are going to have radiation therapy. Trial details Participants will have three marker seeds inserted under local anaesthetic into the prostate before radiotherapy. The seeds are like small rods inserted into the prostate gland and act as ‘landmarks’ so radiotherapy can be given as accurately as possible. All participants will have radiotherapy for 7 weeks. During the 7 weeks of therapy, X-rays will be taken daily for the first 2 weeks to measure the position of the seeds. After that, X-rays will be taken twice a week for 5 weeks to continue to measure the position of the marker seeds. These seeds will stay in your prostate permanently.
Interventions
Nonrandomised study. Three marker seeds will be inserted into the prostate before radiation planning. Using sequential portal films, the seeds can be visualised and measurements will be performed to assess set-up errors over the course of radiation therapy.
The marker seeds will stay in the prostate permanently. The course of radiation therapy will be 7 weeks.
Sponsors
Dr George Hruby
Study design
Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
Male
Age
50 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
all men with clinically localised prostate cancer consented for radiotherapy
Exclusion criteria
on anti-coagulants where ceasing the medications are a cardiovascular risk
Outcome results
None listed