None listed
Conditions
Brief summary
The principal aim of this project is to investigate effects of supplementation with the omega-3 (n-3) polyunsaturated fatty acids (PUFA) EPA and DHA on symptoms of attention deficit hyperactivity disorder (ADHD), specifically hyperactivity, impulsivity, inattention and cognitive problems, in 7-12 year old children. We also aim to investigate blood fatty acid profiles before, during and after the intervention. This 12-month controlled intervention trial will be conducted in Adelaide and Brisbane in 2007/08.
Interventions
This double-blind trial will supplement children with 1g eicosapentaenoic acid (EPA), 1g of docosahexaenoic acid (DHA) or linolenic acid (LA; sunflower oil placebo) in capsule format (4 capsules per day) in a 3 x 3 crossover trial over 12 months. It is expected that 4 months on each oil will provide a sufficient washout from the previous oil.
Sponsors
Nutritional Physiology Research Centre, University of South Australia
Study design
Allocation
Randomised controlled trial
Intervention model
Crossover
Primary purpose
Treatment
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
7 Years to 12 Years
Healthy volunteers
No
Inclusion criteria
Children, ADHD diagnosis, parent-reported learning difficulties, willing to fufil requirements of the study.
Exclusion criteria
Cannot be on stimulant medication, cannot have taken omega-3 supplements for up to 3 months, must not have haemophilia.
Outcome results
None listed