Defining the functional properties of GMP and whey protein study 2007

A 4 week crossover study investigating the effects of whey protein peptides on appetite and food intake in obese individuals

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12607000331437

Acronym

Enrollment

Registered

2007-06-20

Start date

2007-06-13

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study will assess the effects of whey protein and whey protein peptides on food intake, appetite responses and appetite hormones.

Interventions

1 day acute study of 50gm each of 4 treatments given as a drink, whey protein, 2 whey protein peptides compared with a glucose control. Participants consume the drink for one day, then there is a wash-out period of 1 week before crossing over to other arm.

Study design

Allocation

Randomised controlled trial

Intervention model

Crossover

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

Male

Age

20 Years to 65 Years

Healthy volunteers

Inclusion criteria

•Overweight or obese (BMI>25kg/m2) (This will be calculated for you based on your weight (kg) divided by your height in metres squared).•No recent history (past 3 months) of weight loss or changes to diet or physical activity routine.•Unrestrained eater (i.e. restrained eater questionnaire score >10)

Exclusion criteria

•Type 1 or 2 Diabetes•Active liver and kidney disease as noted from medical questionnaire•Current gastrointestinal disease • Past history of gastrointestinal surgery which may affect study outcomes• Hypersensitivity to study foods (milk products)•Medications which affect GI motility or hunger /appetite (e.g.metoclopramide, domperidone and cisapride, anticholinergic drugs (eg atropine), erythromycin)•Unable to comprehend study protocol

Outcome results