Multicentre randomised trial of Anterior 90 degree vs Nissen fundoplication for the treatment of patients with gastro-oesophageal reflux

Conditions

None listed

Brief summary

Random assignment to either Nissen or anterior 90 degree partial fundoplication. Outcome is reflux control and side effects (especially dysphagia). Trial conducted in 6 cities in Australia and New Zealand

Roy Hopkins, Tanya Irvine, G. G. Jamieson, Peter G. Devitt, David I. Watson

British journal of surgery2019-09-1028 citations

10.1002/bjs.11327

Five-year follow-up of a multicenter, double-blind randomized clinical trial of laparoscopic Nissen vs anterior 90 degrees partial fundoplication.

Nijjar RS, Watson DI, Jamieson GG, Archer S, Bessell JR, Booth M, Cade R, Cullingford GL, Devitt PG, Fletcher DR, Hurley J, Kiroff G, Martin IJ, Nathanson LK, Windsor JA, International Society for the Diseases of the Esophagus-Australasian Section.

2010-06-0140 citations

10.1001/archsurg.2010.81

Papers published before 2002-11-01 may not appear yet. Historical indexing is in progress.

Interventions

Anterior 90 degree (oesophagus wrapped 1/4 way around oesophagus) vs Nissen (oesophagus wrapped all the way around oesophagus) fundoplication in patients undergoing surgery for reflux.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

No

Inclusion criteria

Suitable for a laparoscopic Nissen fundoplication

Exclusion criteria

Not suitable for laparoscopic Nissen fundoplicationlarge hiatus herniasevere oesophageal motility disorder

Outcome results