Randomised trial on the efficacy of Ablation vs no Ablation of Barrett's oesophagus with Argon Plasma Coagulation following laparoscopic fundoplication for the reversal of Barrett's oesophagus

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12607000292471

Acronym

Argon Plasma Coaguation post-surgical trial

Enrollment

Registered

2007-06-04

Start date

1999-06-01

Completion date

2018-01-01

Last updated

2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Comparison of Argon plasma Coagulation with surveillance for the reversal of Barrett's oesophagus and the prevention of cancer in the oesophagus

Interventions

Intervention entails coagulating the distal oesophageal mucosa at endoscopy with argon plasma coagulation to try to force conversion of a metaplastic columnar mucosa back to a squamous mucosa.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Prevention

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

Presence of Barrett's oesophagus at endoscopy, previous fundoplication

Exclusion criteria

Reflux not controlled by fundoplication

Outcome results