None listed
Conditions
Brief summary
The primary purpose was to study the efficacy and safety of a new local ointment for the treatment of the severe forms of diabetic foot infection as evidenced by the percentage of patients with healed lesions after 3, 9 and 24 weeks from starting treatment.
Interventions
Sixty patients presented with limb threatening diabetic foot infection were treated with a new local treatment (PEDYPHAR) based on natural product of honey bees (Royal Jelly)1% and panthenol 5%, in an adjusted alkaline ointment base, after good irrigation and cleansing with normal saline. The lesions were occluded with dressing.
Application of the ointment and the dressing was changed daily for the first week, then 3 times per week thereafter,
Duration of intervention was 9 weeks, and all patie
Sixty patients presented with limb threatening diabetic foot infection were treated with a new local treatment (PEDYPHAR) based on natural product of honey bees (Royal Jelly)1% and panthenol 5%, in an adjusted alkaline ointment base, after good irrigation and cleansing with normal saline. The lesions were occluded with dressing. Application of the ointment and the dressing was changed daily for the first week, then 3 times per week thereafter, Duration of intervention was 9 weeks, and all patients were followed up for a period of 6 months.
Sponsors
Dr. Mostafa Yakoot; Dr. Mohamed Etman
Study design
Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Patients presented with limb threatening diabetic foot infection. The lesions were then categorized into 3 main clinical groups we included the group 1 and 2 in analysis (1) skin ulcer (Wagner 1 and 2); (2) deep tissue infection and suspected osteomyelitis (Wagner 3).
Exclusion criteria
We excluded group (3) with gangrenous lesion (Wagner 4 and 5).
Outcome results
None listed