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Transthoracic Echocardiography and Transurethral Resection of the Prostate

High dose versus low dose fluid preloading and the effect on left ventricular volume and function prior to the administration of spinal anaesthesia in patients undergoing transurethral resection of the prostate.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12607000207415
Enrollment
60
Registered
2007-04-13
Start date
2007-04-02
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The primary purpose of this study is to find out what dose of intravenous fluid maintains enough fluid volume in the body after a spinal anaesthetic. Particpiants in this study are randomly assigned to have a high dose of intravenous fluid or a low dose of intravenous fluid. We find out how much fluid is in the body by doing an ultrasound of the heart before the the intravenous fluid is given, after the intravenous fluid is given, after the spinal anaesthetic is given and at the end of the operation.

Interventions

All patients receive 5 ml/kg of 0.9% sodium chloride as a standard fluid loading regime. The intervention group receives a further 10 ml/kg of 0.9% sodium chloride intravenously. The intravenous fluid is administered until each patient has reached the specific amount calculated by thier weight. The spinal anaesthesia is performed once the fluid loading and the transthoracic echocardiography has been completed.

Sponsors

Department of Anaesthesia St Vincent's Hospital Melbourne
Lead SponsorHospital

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)

Eligibility

Sex/Gender
Male
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

Patients undergoing elective transurethral resection of the prostate.

Exclusion criteria

Patients with contraindications to spinal anaesthesia. Patients who require invasive cardiac monitoring.

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026