None listed
Conditions
Brief summary
The primary purpose is to evaluate the effectiveness of a walking program, especially the ‘dose’ of walking necessary to elicit clinically significant improvements in well-being among individuals aged 40 to 75 years with early osteoarthritis (OA) and test whether walking combined with glucosamine offers improvements. Improvements in well-being are defined as reductions in pain, stiffness, depression and anxiety and increases in functional ability, and self-efficacy towards exercise.
Interventions
18-week, unsupervised home-based progressive walking program performed at the convenience of paticipants schedule.
18-week oral glucosamine sulphate supplementaion (1500 mg daily).
Participants were recruited from the Greater Brisbane area through flyers, television, radio, surveys and various seniors' events.
Feasibility trial.
No control group.
Two treatment groups:
Group 1: 18-week walking program, 3 days per week, starting with 1500 steps in the first week and finishing with 6000 steps
18-week, unsupervised home-based progressive walking program performed at the convenience of paticipants schedule. 18-week oral glucosamine sulphate supplementaion (1500 mg daily). Participants were recruited from the Greater Brisbane area through flyers, television, radio, surveys and various seniors' events. Feasibility trial. No control group. Two treatment groups: Group 1: 18-week walking program, 3 days per week, starting with 1500 steps in the first week and finishing with 6000 steps by week 18, and 18-week oral glucosamine sulphate supplementation (1500 mg daily) Group 2: 18-week walking program, 5 days per week, starting with 1500 steps in the first week and finishing with 6000 steps by week 18, and 18-week oral glucosamine sulphate supplementation (1500 mg daily)
Sponsors
University of Queensland
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
Experience pain in at least one knee or hip, - Experience morning stiffness in that knee or hip in the past month- Experience difficulty with performing activities of daily living such as rising from a chair, getting out of bed and other self-care activities- Plan to live in the Greater Brisbane area over the next 6 months- Not exercising more than 60 mins per week- Not allergic to shellfish.
Exclusion criteria
Corticosteroid or viscosupplement injections in the previous 3 months- Secondary forms of OA in the study knee or hip- Chondrocalcinosis in the study knee or hip- Concomitant inflammatory arthritis or metabolic arthritis- Infected knees or hips- Having a co-morbidity precluding safe involvement in exercise - Living in a dependent environment such as a nursing home- Participation in another research study- Plans for surgery during the study period- For women, pregnant or planning to become pregnant over the next year- Receiving psychiatric or psychological treatment (counselling or pharmacological)- The inability to walk at least 15 minutes continuously.
Outcome results
None listed