Alerting deficits in Children with Attention Deficit/Hyperactivity Disorder(ADHD) Revealed by functional Magnetic Resonance imaging(fMRI)

Naturalistic observation for alerting deficits in Children with Attention Deficit/Hyperactivity Disorder (ADHD) compare with normal controls by performing a cued target detection task during functional Magnetic Resonance imaging (fMRI)

Status

Completed

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12607000079448

Enrollment

Registered

2007-01-23

Start date

2005-02-12

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The aim of this study is to investigate the alerting functions deficits in children with ADHD using functional magnetic resonance imaging during the state of nature. We expect that the parietal lobe of ADHD showed lower activities than normal controls and the ADHD symptoms severity for inattention maybe correlate with the activities of parietal lobe in children with ADHD. This study will help us to further understand the pathology of ADHD.

Interventions

During the state of nature (without any treatment or intervenes), 15 children with ADHD aged 11-16 years old, were asked to carry out a cued target detection task, in which participants were asked to respond to a white dot target, which could or could not be preceded by a star cue, during fMRI. The task lasted about 20 minutes.

Eligibility

Sex/Gender

Male

Age

11 Years to 16 Years

Healthy volunteers

Inclusion criteria

1) right-handed, 2) Combined subtype of Attention Deficit/Hyperactivity Disorder (ADHD-C) or Attention Deficit/Hyperactivity Disorder predominantly inattentive type (ADHD-I)) and normal controls, 3) no history of emotional disorders, affective disorders, Tourette disorder and other Axis?psychiatric disorder.

Exclusion criteria

The full scores of Wechsler Intelligence Scale for Chinese Children-Revised lower than 85.

Outcome results