Effects of calcium and vitamin D supplementation on bone mineral density and bone related chemistry in elderly women

A 5-year randomised controlled trial of the effects of calcium and vitamin D supplementation on bone mineral density and bone related chemistry in elderly ambulant Australian women

Status

Completed

Phases

Phase 2

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12607000055404

Enrollment

120

Registered

2007-01-17

Start date

1998-07-21

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This is a 5-year randomised, double blind, placebo controlled study to evaluate the relative benefits of vitamin D and calcium supplementation and calcium alone compared to placebo on hip bone mineral density and bone related biochemistry in ambulant elderly Western Australian women aged 70-80 years at baseline.

Interventions

This was a 5-year randomised, controlled, double-blind study. Participants were randomised to orally receive either 1000 IU ergocalciferol and 1200 mg calcium (Ca) in the form of carbonate (CalD group), 1200 mg Ca and placebo vitamin D (Ca group) per day over the 5 years.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Prevention

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

70 Years to No maximum

Healthy volunteers

Inclusion criteria

Likely to survive a five-year study.

Exclusion criteria

Receiving bone active agent. There were no other specific exclusions so that the results could be generalised to the whole ambulant population.

Outcome results