Chlorhexidine in preterm babies

Use of chlorhexidine as a topical antiseptic for the prevention of nosocomial sepsis in premature neonates < 29 weeks: a blinded randomised controlled trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12607000050459

Enrollment

169

Registered

2007-01-16

Start date

2005-04-04

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Strategies for reducing infection are vital in caring for the premature neonate, and include, the use of a topical antiseptic for skin cleansing prior to any invasive procedure that compromises the skin barrier. There is currently little research addressing the issue of what antiseptic solution is best and safest for use in this vulnerable neonatal population. Consequently a wide range of solutions are utilised within the NICU setting

Interventions

Aqueous chlorhexidine 0.5% (intervention group) applied topically. The solution is applied prior to each invasive procedure for both control and intervention groups.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Prevention

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

0 to 29 Weeks

Healthy volunteers

Inclusion criteria

Inborn infants < 29 weeks. Informed parental consent.

Exclusion criteria

Parental consent not given. Ex utero transfer, unlikely to survive major congenital anomaly.

Outcome results