None listed
Conditions
Brief summary
In people with medial knee osteoarthritis, a 12-week program of strengthening the hip abductor and adductor muscles will reduce knee loading during walking gait, as measured by a reduction in the knee adduction moment.
Interventions
People will be screened via telephone and undergo radiographic evaluation. Baseline testing will be performed at the University of Melbourne and the participant randomised into one of two groups: (i) hip strengthening; (ii) no strengthening control. The intervention will last for 12 weeks after which all participants will be reassessed by the same blinded assessor.
The exercise intervention will comprise 7 visits over 12 weeks to one of 7 physiotherapists located around Melbourne plus home ex
People will be screened via telephone and undergo radiographic evaluation. Baseline testing will be performed at the University of Melbourne and the participant randomised into one of two groups: (i) hip strengthening; (ii) no strengthening control. The intervention will last for 12 weeks after which all participants will be reassessed by the same blinded assessor. The exercise intervention will comprise 7 visits over 12 weeks to one of 7 physiotherapists located around Melbourne plus home exercises five times weekly. A comprehensive exercise manual will be produced. Programs comprise standardized progressive strengthening exercises but the physiotherapist will individually determine the repetitions (up to 10), sets (up to 2) and resistance depending on the person’s pain level and response. Resistance will be obtained from cuff weights to the ankle and theraband. These will also be provided for home use. The exercises will comprise sidelying hip abduction, hip abduction and adduction in standing with theraband, and isometric hip adduction squeezes.
Sponsors
Prof Kim Bennell
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Eligibility will be confirmed by radiographic and clinical examination. Medial tibiofemoral joint osteoarthritis (OA) fulfilling American College of Rheumatology classification criteria and reporting average knee pain on walking >3 on an 11-point scale will be included. Other inclusion criteria will be: (i) varus knee malalignment on standing anteroposterior lower limb x-ray.
Exclusion criteria
(i) knee surgery or intra-articular corticosteroid injection within 6 months; (ii) current or past (within 4 weeks) oral corticosteroid use; (iii) systemic arthritic conditions; (iv) history of tibiofemoral/patellofemoral joint replacement or tibial osteotomy; (v) any other muscular, joint or neurological condition affecting lower limb function; (vi) back or hip pain within the past 3 years that caused the patient to seek treatment, take medication, miss work or interfere with function for at least one week; and (vii) any physiotherapy or lower limb strengthening exercises in the past 6 months.
Outcome results
None listed