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Transfer of preterm infants from incubator to open cot at a lower body weight (1600g) versus a higher body weight (1800g)

A randomised controlled trial of transferring preterm infants born less than 1600g, from incubator to open cot at lower (1600g) versus higher (1800g) body weight to determine the effects on weight gain, temperature stability and length of hospital stay

Status
Completed
Phases
Phase 3
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12606000518561
Acronym
TIC
Enrollment
182
Registered
2003-08-26
Start date
2003-07-07
Completion date
2009-02-13
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

One of the key criteria for discharging preterm infants from nurseries is their ability to maintain their temperature once transferred from an incubator to an open cot. This practice varies widely between neonatal units; however it seems that a weight mark of 1800g is preferred, which appears to be based on tradition or the personal experience of clinicians, as the scientific evidence of when and at what weight this should occur is limited. By delaying transition to an open cot on the basis that the infant has not reached a certain weight may result in longer hospitalisation than necessary, thus increasing cost of care and prolonging parental separation resulting in parental anxiety. However, transferring infants too soon may also result in extended hospitalisation and again add to cost of care. This study will determine the effects of transferring preterm infants from incubators to open cots at a lower weight of 1600 grams on the outcomes of temperature stability, weight gain and length of hospital stay.

Interventions

intervention group- will remain in the incubator until the weight reaches greater than or equal to 1600 grams at which time they will be transferred to and nursed in an open cot until discharge

Sponsors

Division of neonatology, Royal Brisbane & Women's Hospital
Lead SponsorHospital

Study design

Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)

Eligibility

Sex/Gender
All
Age
2 Days to No maximum
Healthy volunteers
No

Inclusion criteria

Preterm infants, both male and female, with a birthweight of less than 1600 grams - weight <1600 grams at enrolment- >=48 hours age,- >= 48 hours without requiring assisted ventilation or Continuous Positive Airway Pressure (CPAP)- medically stable- receiving enteral calorie intake of at least 60 mls/kg/day, and- at least one parent who can understand written or spoken English.

Exclusion criteria

Requiring assisted ventilation or CPAP,- medically unstable,- oxygen via cot or sub nasal prongs,- major congenital abnormality.

Outcome results

None listed

Source: ANZCTR · Data processed: Mar 28, 2026