Parecoxib for postoperative pain after minor gynaecological surgery

Single dose parecoxib for pain relief following dilatation and curettage and/or hysteroscopy

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12606000480583

Acronym

The COMFIT study

Enrollment

Registered

2006-11-23

Start date

2006-09-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study aims to find out if giving a single dose of parecoxib intravenously in theatre improves pain relief following surgery for dilatation and curettage with or without hysteroscopy.

Interventions

Randomised double blind placebo-controlled parallel group study of a single intraoperative dose of intravenous parecoxib 40 mg versus saline placebo

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

American Society of Anesthesiologists (ASA) physical status classifiaction I or II Undergoing dilatation and curettage +/- hysteroscopy

Exclusion criteria

Renal dysfunction Hypertension History of sulphonamide allergy Unsuitable for general anaesthesia with maintenance by inhalational agent Use of suxamethonium Preoperative use of NSAID or opiate analgesics

Outcome results