None listed
Conditions
Brief summary
4 month diet and and exercise program. Pre and Post ssessment of anthropometry, sleep disordered breathing, cardiovascular fitness, muscle strength, blood pressure, glucose.
Interventions
4- Month Diet and Exercise Program
1. Diet - 8 weeks total food replacement with a very low calorie liquid food replacement, followed by 4 weeks with 2 meals replaced, then 4 weeks with 1 meal replaced with the very low calorie liquid food replacement.
2. Exercise - 3 exercise sessions per week for the first 8 weeks, supervised in the hospital gymnasium, plus an at-home exercise program. After these first 8 weeks, the supervised exercise sessions are gradually reduced and replaced with home exce
4- Month Diet and Exercise Program 1. Diet - 8 weeks total food replacement with a very low calorie liquid food replacement, followed by 4 weeks with 2 meals replaced, then 4 weeks with 1 meal replaced with the very low calorie liquid food replacement. 2. Exercise - 3 exercise sessions per week for the first 8 weeks, supervised in the hospital gymnasium, plus an at-home exercise program. After these first 8 weeks, the supervised exercise sessions are gradually reduced and replaced with home excercise program. Each exercise session comprises both aerobic and resistance training, and lasts for 30 - 60 minutes.
Sponsors
Physiotherapy Foundation
Study design
Allocation
Non-randomised trial
Intervention model
Single group
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Obstructive Sleep ApnoeaObesity, with waist circumference at least 100cm for men and 95cm for women
Exclusion criteria
Severe sleep-disordered breathing with signfiicant sleep hypoxaemia or dangerous daytime sleepinessMusculoskeletal abnormalities which preclude moderate exercise.Other significant medical or psychological illnesses, in particular diabetes, liver or kideny disease.
Outcome results
None listed