Prenatal diagnosis of Down's Syndrome using isolation of foetal cells from cervical mucous and peripheral blood during first trimester of pregnancy

Prenatal diagnosis of Down's Syndrome using isolation of foetal cells from cervical mucous and peripheral blood during first trimester of pregnancy in women

Status

Withdrawn

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12606000460505

Acronym

NPD

Enrollment

2000

Registered

2006-11-02

Start date

2007-02-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The trial is to investigate novel non-invasive methods for the prenatal diagnosis of Down Syndrome by isolation of foetal cells from peripheral blood and cervical mucous.

Interventions

A single peripheral blood sample obtained by venupuncture at 10-12 weeks gestation, immediately prior to CVS. A single cervical mucous sample obtained by aspiration catheter at 10-12 weeks gestation, immediately prior to CVS. The whole period of the study is 24 months.

Study design

Allocation

Non-randomised trial

Intervention model

Parallel

Primary purpose

Diagnosis

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Healthy volunteers

Inclusion criteria

Pregnant women presenting for Chorionic Villous Sampling.

Exclusion criteria

Pregnant women not requiring an invasive test.

Outcome results