None listed
Conditions
Brief summary
The study is designed to provide evidence of whether patients with heart failure and obstructive sleep apnoea gain benefit from Continuous Positive Airway Pressure treatment not only in terms of treating Obstructive Sleep Apnoea but on heart function as well. The study hypothesis is that CPAP will have a beneficial effect on heart function as measured by an increase in left ventricular ejection fraction.
Interventions
Non randomised parallel study. Intervention group: Continuous positive airway pressure (CPAP) device used for treating obstructive sleep apnoea to be used each sleeping period at home. This is a standard treatment device for treating obstructive sleep apnoea. It involv
Non randomised parallel study. Intervention group: Continuous positive airway pressure (CPAP) device used for treating obstructive sleep apnoea to be used each sleeping period at home. This is a standard treatment device for treating obstructive sleep apnoea. It involves sleeping with a nasal or full face mask attached to the pressure machine. The pressure is individually determined for each subject via titration. Duration for both groups 6 months.
Sponsors
Otago University
Study design
Allocation
Non-randomised trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Adults with heart failure (Left ventricular ejection fraction < 45%) and Obstructive Sleep Apnoea (Apnoea/hypopnoea index > 10/hr).
Exclusion criteria
Renal failure, respiratory failure, pyschiatric history, alcohol dependancy.
Outcome results
None listed