Group Cognitive Behavioural Therapy (CBT) and Mindfulness-Based Cognitive Therapy (MBCT) for depression

Predictors of improvement and mechanisms of change in group Cognitive Behaviour Therapy (CBT) and Mindfulness Based Cognitive Therapy (MBCT) for depression: a two stage study

Status

Completed

Phases

Phase 1

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12606000402549

Enrollment

190

Registered

2006-09-13

Start date

2006-10-10

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study aims to examine the effectiveness of group Mindfulness-Based Cognitive Therapy (MBCT) and standard Cognitive Behavioural Therapy (CBT) as treatments for depression as well as examine the mechanisms of change and predictors of change in both groups. Depressed participants will be recruited and randomly assigned to receive one of the group programs. Both programs will run for 2.5 hours a week for eight weeks. Participants will receive a clinical assessment prior to randomisation and will complete a number of questionnaires before and after the group program and at follow-up assessments at 6 and 12 months. The first pilot phase of the study will assess feasibility and likely effectiveness of MBCT, and pending results will be followed by the second main phase of the study.

Interventions

Participants who are experiencing depression will be randomly allocated to either the Cognitive Behavioural Therapy or Mindfulness-Based Cognitive Therapy. Both groups will run for 8 weeks for 2.5 hours per session. Both groups will be faciliated by trained and registered psychologists.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Diagnostic and Statistical Manual of Mental Disorders-IV (DSM-IV) criteria for Major Depressive Disorder /Dysthymis (Composite International Diagnostic Interview assessment)Score 19 or more for Beck Depression Inventory and 12 or more for HAMDMust have been depressed for at least 3 months (no upper limit)Proficiency in EnglishNo prior history of Cognitive Behavioural Therpay or formal training in Mindfulness or meditation/relaxation (operationalised as more than 4 sessions or regular meditation/relaxation) and not currently receiving psychological therapyMust have a case manager/clinicianNot currently on antidepressants, or have not changed their medication regimen over the last three months but remain significantly depressedCommitment to an 8 week program

Exclusion criteria

Melancholic Depression (currently)History of any psychotic illnessDementiaCurrent suicidal ideationInpatient statusConcurrent treatment using meditation or Cognitive Behavioural TherapyDrug/alcohol dependenceDaytime anxiolytic medication (sedatives at night OK)Bipolar DisorderAntenatal or postnatal depressionAntipsychotics or mood stabilisersHave been treated with more than 2 antidepressants previously.

Outcome results