Hepatitis B immunity and response to a booster dose of hepatitis B vaccine in Indigenous children who recieved hepatitis B vaccines in infancy

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12606000396527

Acronym

Long term hepatitis B immunity

Enrollment

450

Registered

2006-09-11

Start date

2006-04-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Adolescent enrolled in the Aboriginal Birth Cohort Study will have their serology to hepatitis B measured. Adolescents who received hepatitis B vaccines in infancy and have low immunity will be offered booster doses of the vaccine and have their immunity measured 2-4 weeks post vaccination.

Interventions

Adolescents with low immunity will be offered booster doses of the vaccine and have their immunity measured 2-4 weeks post vaccination. HBVaxII 10microgram dose vaccine will be administered intramsucularly in this study Study duration is 1 month approximately

Study design

Allocation

Non-randomised trial

Intervention model

Single group

Primary purpose

Prevention

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

16 Years to 19 Years

Healthy volunteers

Inclusion criteria

Enrolled in the Aboriginal Birth Cohort (ABC).

Exclusion criteria

Not enrolled in original Aboriginal Birth Cohort StudyAll participants have their hepatitis B serology measured at baselineBooster vaccination for only those whose HBsAb level <10 IU/ml.

Outcome results