Long term hepatitis B immunity and response to a booster dose of hepatitis B vaccine in children born to hepatitis B carrier mothers

Hepatitis B immunity and response to a booster dose of hepatitis B vaccine in children born to hepatitis B carrier mothers

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12606000394549

Enrollment

150

Registered

2006-09-07

Start date

2005-12-10

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Hepatitis B serology will be measured in children born to hepatitis B carrier mothers. Those with low immunity will be given a booster dose of hepatitis B vaccine and have their immunity measured post vaccination

Interventions

Hepatitis B serology at baseline Response to a booster dose of hepatitis B vaccine HBVaxII 10microgram intramuscularly

Study design

Allocation

Non-randomised trial

Intervention model

Single group

Primary purpose

Prevention

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

10 Years to 19 Years

Healthy volunteers

Inclusion criteria

Adolescents born to hepatitis B carrier mothers.

Exclusion criteria

Mother not a hepatitis B carrierAll participants have hepatitis B serology at baselineOnly adolescents with HBsAb <10IU/ml given a booster dose of vaccine.

Outcome results