None listed
Conditions
Brief summary
This study tests whether d-cycloserine improves the effectiveness of exposure therapy for decreasing social anxiety symptoms. We predict that individuals from the community diagnosed with social phobia who receive four exposure therapy sessions in comdination with D-Cycloserine will experience a greater reduction in social anxiety symptoms than individuals who receive placebo in combination with four exposure therapy sessions. Participants receive five weekly group therapy sessions. the first session is educational and the next four consist of public speaking exposure therapy. One month post intervention participants are assessed for social anxiety symptoms as well as other general health indicators. All subjects, therapists, assessors and data entry research staff are blind to condition.
Interventions
Participants with social phobia are given exposure therapy over 5 once per week weekly treatment sessions in combination with D-cycloserine (50mg) in capsule form to be swallowed orally. Exposure therapy consists of 3 to 10 minute speech tasks in front of a group (some decrease in anxiety should be observed).
Sponsors
University of New South Wales
Study design
Allocation
Randomised controlled trial
Intervention model
Parallel
Primary purpose
Treatment
Masking
Blinded (masking used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Primary diagnosis of Social Phobia.
Exclusion criteria
Epilepsy, severe kidney disease, Suicide intent, substance dependence, use of contra-inidcated medications, pregnancy.
Outcome results
None listed