None listed
Conditions
Brief summary
Patients receiving intravenous chemotherapy may require a central venous catheter (CVC) to enable effective delivery of the cytotoxic treatment. This is usually because of either difficult peripheral venous access or prolonged infusional chemotherapy schedules. This study is a randomised clinical trial comparing two types of CVC, the peripherally inserted central venous catheter (PICC) and the subcutaneously implanted port catheter (PORT catheter). The primary end point is CVC related complications. Background The last three decades have seen an increase in the use of chronic indwelling central venous catheter devices (CVC) in the setting of cancer treatment. CVCs enable effective delivery of chemotherapy into the venous system, and are particularly useful when peripheral venous access is otherwise difficult or when prolonged infusions of chemotherapy are required. The CVC also facilitates outpatient based therapy.
Interventions
Comparison of peripherally inserted central venous catheter (PICC) versus subcutaneoulsy implanted port catheters (PORT) Both these Central venous catheters (CVC) can be removed at the end of chemotherapy. Chemotherapy duration can range from 6 weeks to 6 months.
Sponsors
Flinders Medical Centre
Study design
Allocation
Randomised controlled trial
Intervention model
Other
Primary purpose
Treatment
Masking
Open (masking not used)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1.All patients with cancer (excluding leukaemia and myeloma) who require chemotherapy administration through a CVC2.Minimum anticipated duration of CVC directed therapy is 1 month (30 days).3. Patients should have a projected life expectancy of at least 3 months5.Written informed consent.
Exclusion criteria
1.Inability to provide informed consent2.Any contraindication to insertion of either PICC or PORT catheter3.Anticipated inability to follow-up patient for CVC care4.Previous participation in this trial (ie the same patient cannot be entered twice into the trial in the event that the original CVC is removed and another CVC is to be inserted).5.Patient to receive high dose chemotherapy and stem cell or bone marrow transplantation.
Outcome results
None listed