Zinc supplementation in asthma

The effect of oral Zinc supplementation in asthma in reducing the dose of inhaled steroids

Status

Not yet recruiting

Phases

Phase 3

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12606000149561

Acronym

OZSA

Enrollment

Registered

2006-05-01

Start date

2006-05-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Hypothesis: Zinc deficiency potentiates airway inflammation in asthma. This study is to determine if oral zinc supplementation will improve asthma control to enable a reduction in the maintenance dose of inhaled steroids. Blinding is for subjects & assessors.

Interventions

Oral Zinc 50 mg Zn daily for 4 months

Study design

Allocation

Randomised controlled trial

Intervention model

Crossover

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Persistent asthma: on 400ug of budesonide or equivalent toachieve good to moderate asthma control.

Exclusion criteria

Prednisolone or exacerbation within 3 months :smoking in last 2 years.

Outcome results