Renal impairment in decompensated heart failure.

A longitudinal cohort study to describe the severity, incidence, nature, and evolution of renal impairment over 12 months in individuals hospitalised with decompensated heart failure.

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12606000137594

Acronym

Nil

Enrollment

120

Registered

2006-04-20

Start date

2006-07-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This is an observational study of individuals who require hospital admission for severe heart failure. At admission and at 6 and 12 months of community follow up detailed measurement of both heart and kidney function will describe the nature, severity and frequency of kidney failure. The study aims to determine the important predictors of kidney impairment in severe heart failure.

Interventions

This is a longitudinal prospective cohort study of individuals hospitalised with decompensated heart failure. Unselected consecutive patients admitted to a tertiary hospital with the primary diagnosis of heart failure will be followed for 12 months. Renal function (measured glomerular filtration rate) and renal blood flow will be measured at selected timepoints during admission and at 6 months, concurrent with detailed measurements of cardiac status (echocardiogram and neurohormonal profile).

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1) All individuals hospitalised at a tertiary-level hospital with the primary diagnosis of decompensated heart failure.

Exclusion criteria

1) Severe stenotic valvular disease2) Women of childbearing age3) Exposure to iodinated contrast during the hospital admission4) Contraindication to magnetic resonance imaging.

Outcome results