Weight Loss & Cardiovascular Risk in Type 2 Diabetes Study

Effect of energy restriction and exercise training on flow-mediated dilatation and oxidative stress in sedentary overweight and obese subjects with type 2 diabetes

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12606000107527

Acronym

n/a

Enrollment

Registered

2006-03-23

Start date

2006-03-06

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

The principal aim of this research project is to determine the separate effects of energy restriction/weight loss and aerobic exercise training on blood vessel function in sedentary overweight and obese subjects with type 2 diabetes. It is a secondary aim to evaluate whether physical exercise training and weight loss will enhance antioxidant capacity, reduce oxidative stress and increase nitric oxide bioavailability

Interventions

12 weekdietary weight loss (energy restriction) & aerobic exercise training program

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Treatment

Masking

Open (masking not used)

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Healthy volunteers

Inclusion criteria

BMI greater than 27, less than 40Type 2 diabetes.

Exclusion criteria

Beta-blocker or glucocortcoids medicationdietary supplementsregular physcial exercise.

Outcome results