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Effect of epidural adenosine and neostigmine on postoperative pain status

A randomised study to evaluate the effect of epidural adenosine and neostigmine in patients undergoing abdominal surgery to improve postoperative pain status.

Status
Completed
Phases
Unknown
Study type
Interventional
Source
ANZCTR
Registry ID
ACTRN12606000043538
Enrollment
40
Registered
2006-01-27
Start date
2003-01-01
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

To examine whether the epidural adenosine enhance the antinociceptive effect of neostigmine, we evaluated the effect of epidural co-administration of neostigmine and adenosine in patients undergoing abdominal surgery.

Interventions

Epidural adenosine and neostigmine for 4 hours given as intravenous injections over 12 weeks

Sponsors

Eiji Masaki
Lead SponsorIndividual

Study design

Allocation
Randomised controlled trial
Intervention model
Single group
Primary purpose
Treatment
Masking
Blinded (masking used)

Eligibility

Sex/Gender
All
Age
0 to No maximum
Healthy volunteers
No

Inclusion criteria

Patients undergoing lower abdominal surgery for benign gynecological disease.

Exclusion criteria

No exclusion criteria

Outcome results

None listed

Source: ANZCTR · Data processed: Feb 4, 2026