A study on the effectiveness of an oxygen delivery system.

Evaluation of the Fisher and Paykel high flow humidified nasal interface system by the measurement of hypopharyngeal inspired oxygen fraction and airway pressures in healthy volunteers.

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12605000798662

Enrollment

Registered

2005-12-20

Start date

2006-01-04

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

It is likely that high flow nasal systems are able to deliver a more constant and reliable FiO2 than traditional methods. Our proposed method of measurement of FiO2 is through the insertion of a nasopharyngeal catheter and continuous measurement of end expired oxygen (FETO2) and carbon dioxide (FETCO2) fractions. Measurements of FiO2 will be made with increasing gas flow rates, inspiratory flow rate (with exercise) and during mouth and nose breathing.

Interventions

A study to find the flow rate which enables the delivery of a desired inspired oxygen fraction (FiO2) in healthy volunteers. Each participant will have a nasopharyngeal catheter inserted, then they will be started on oxygen through the Fisher and Paykel high flow humidified nasal interface system (MR880, RT241, RT033/034). FiO2 at different flow rates will be calculated from measured end expired oxygen (FETO2) and carbon dioxide (FETO2) fractions. Measurements will be made at rest with quiet br

Study design

Allocation

Non-randomised trial

Intervention model

Single group

Primary purpose

Treatment

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

Fit Healthy Adult Volunteers.

Exclusion criteria

1. Pregnancy. 2. Abnormal upper airway anatomy. 3. Recent (within 1 week) or current upper or lower respiratory tract infection. 4. Chronic respiratory illness. 5. Any medical condition precluding the ability to exercise eg. exercise induced asthma, ischaemic heart disease, hypertrophic obstructive cardiomyopathy.

Outcome results