Effect of TIVA versus Sevoflurane on the incidence of post operative nausea and vomiting following day case gynaecology surgery

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12605000796684

Enrollment

130

Registered

2005-12-16

Start date

2006-11-01

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

Rational for project Many studies have investigated the treatment of post operative nausea and vomiting (PONV) However, there is disagreement on both the incidence of PONV and how to prevent it Few studies have investigated the period post discharge Day case gynaecological surgery patients are particularly at risk of PONV There is evidence that total intravenous anaethesia may decrease the incidence of PONV This study sets out to investigate a specific subgroup of high risk patients. This will allow for specific recommendations to be made regarding the management of this subgroup of patients.

Interventions

Total intravenous anaesthetic. Prospective randomised trial. Patients stratified into high and low risk. The trial is to run over approximately 12 months.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Prevention

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

General anaesthetic. Day case gynaecology surgery.

Exclusion criteria

ASA IV or V, allergies to study medication, pregnancy, breast feeding, psychiatric illness, epidurals, planned admission.

Outcome results