Psychological factors and response to medical treatment: Do psychological factors determine the outcome in patients with inflammatory bowel disorders and other common gastrointestinal and hepatologic disorders?

The course of inflammatory bowel disease, irritable bowel syndrome and hepatitis C in relation to psychological co-morbidity - a cohort prospective management trial.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ANZCTR

Registry ID

ACTRN12605000752662

Enrollment

275

Registered

2005-11-17

Start date

2005-11-20

Completion date

Unknown

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

To observe and compare the course of IBD, IBS and hepatitis C in relation to psychological co-morbidity.

Interventions

Study was a cohort prospective management study. This design enabled a comparison of the rates of psychological disorders and quality of life in IBD, IBS and HCV patients over a one-year period. The study aimed to establish whether psychological co-morbidities affect the likelihood of a successful response to treatment.

Eligibility

Sex/Gender

All

Age

0 to No maximum

Healthy volunteers

Inclusion criteria

Participants who visit the Department of Gastroenterology in Royal Adelaide Hospital (RAH) between November 2005 and April 2006 will be recruited consecutively by their doctors from IBD, IBS and Hepatitis C outpatients. Patients will be informed about the research and written consent will be obtained. Inclusion criteria Patients included into studies must satisfy any one of 1-3 AND both of 4 & 5(1) Patients with IBD (Crohns disease or ulcerative colitis) diagnosed by clinical, endoscopic, histologic and/or radiologic criteria; (2) Patients with IBS diagnosed by clinical, endoscopic, histologic and/or radiologic criteria;(3) Patients diagnosed serologically with hepatitis C;(4) Patients with sufficient knowledge of English to understand and answer questionnaires;(5) Patients who sign written informed consent.

Exclusion criteria

(1) Patients with insufficient knowledge of English or who are cognitively impaired, as the study requires filling in and understanding questionnaires written in English;(2) Patients who do not give informed consent;(3) Hepatitis C patients with cirrhosis (other than Childs A) or cancer of the liver as, this may be confounding psychological factors, due to disease severity/known effect on mortality.

Outcome results