The effects of sleep deprivation and dexamphetamine on driving, neuropsychological function and brain activity in professional drivers

Status

Completed

Phases

Phase 1

Study type

Interventional

Source

ANZCTR

Registry ID

ACTRN12605000730606

Acronym

SPEED SLEEP

Enrollment

Registered

2005-11-11

Start date

2004-06-01

Completion date

2007-06-22

Last updated

2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Brief summary

This study reported on driving and vigilance after 27-h of sleep deprivation in professional drivers. The study is completed.

Interventions

A group of current amphetamine users will undergo 4 sessions, 2 sleep deprived and 2 at rest, each with a placebo and dexamphetamine condition. A group of non-users will undergo 2 sessions, 1 sleep deprived and 1 at rest.

Study design

Allocation

Randomised controlled trial

Intervention model

Parallel

Primary purpose

Educational / counselling / training

Masking

Blinded (masking used)

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

(Control group): Curent drivers license. Not used amphetamine within last 10 years. (Users group): Current drivers license. Currently use amphetamine.

Exclusion criteria

History of cardiovascular disease, hypertension, epilepsy, diabetes, psychiatric illness; heavy Smokers; 5 or more caffienated beverages per day; Visual impairment that does not correct with glasses; English not first language.

Outcome results